MENTABOLANAKA 

7a-methyl-19-norandrostenedione, Mentabolan, MENT dione, Trestione.

A brand new prohormone from Prohormone Forum/IBE. It was synthesized and tested for anabolic and androgenic activity in 1963.This compound is a "19-nor", or nandrolone derivative, and differs from nandrolone in that this hormone has a 17-ketone, where nandrolone has a 17b-hydroxy function, and also has the addition of a 7a-methyl group. 

In the same way as "Boladrol" is a 7a-methylated dione version of methyl testosterone, this compound is a 7a-methylated dione version of nandrolone.Effects should be similar to the injectable trestolone acetate. It's a strongly anabolic, moderately androgenic compound which should elicit significant strength gains and increased muscle mass at an appropriate dosage.

Side-effects may include those common to anabolic androgenic steroids, including but not limited to: blood pressure increases, HPTA disruption, adverse shifts in lipoprotein subfractions (increased HDL, lowered LDL cholesterol), acne, hair growth or loss. This product should not be used by women or teens. There's evidence of aromatization to some degree, so the gyno-prone may wish to either avoid this compound or co-administer an aromatase inhibitor (AI) or selective estrogen receptor modulator (SERM) while using it.

One side-effect that many might fear from this compound is the loss of libido and/or erectile dysfunction often seen with 19-nor derivatives. Tests conducted with the target hormone trestolone (MENT) have found that it had a positive mood, libido, and erection-stimulating effect similar to that of testosterone, though this may not necessarily hold true with the supraphysiological doses used by bodybuilders.This is a "dione" prohormone. In the body, the ketone at C17 will be hydrolysed by 17b-hydroxysteroid dehydrogenase type 1 (17b-HSD1) into the active compound trestolone (MENT). Trestolone itself has been shown to be roughly 6 times as anabolic as methyl test by oral administration, and around 2.5 times as androgenic. Trestolone shows no affinity for SHBG, so all of the converted compound in circulation should be bioavailable. For the same reason, it's likely to have a short terminal half-life so frequent dosing is suggested.

Testosterone and similar delta-4 steroids are typically converted to stronger compounds like DHT and DHT derivatives by the enzyme 5-alpha reductase (5AR). 19-nor compounds are an exception to this rule, with 5a-reduced nandrolone (or 19-nor DHT) being a far less potent androgen than nandrolone itself. The 7a-methylation of trestolone hinders the reduction of this double bond, so delta 5(10) isomers are a major excreted metabolite. This means the 7a-methyl group not only makes the compound stronger by increasing androgen receptor affinity, but also reduces the ability of the body's enzymes to break it down into weaker metabolites. The addition of the 7a-methyl group has a flattening effect on the molecule which improves androgen receptor binding. MENT is a strong compound for several reasons, but the primary reason for its strength is the increased androgen receptor affinity caused by the conformational changes of the 7a-methyl group.

CYANOSTANE (Also called Cynabol)

Cyanostane is a new prohormone which features an alteration of the superdrol compound, with a cyano bond instead of the 2a methyl superdrol bond. 

It's relatively new with few reviews. The chemical structure is the same as methyldrostanolone (Superdrol), except it has a cyano group on the 2 position instead of a methyl group. It is a C-17aa steroid and it will be liver toxic, although, due to the lack of the 4-ene on ring A and lack of 2-methylation, liver toxicity may be reduced relative to a di-methylated steroid such as Superdrol. 

Expected results would be lean gain as this compound cannot convert to estrogen. Based on the chemical structure the anabolic potency would appear to be fairly potent with moderate androgenic potency. There seems to be a nomenclature mistake on the labeling for this steroid. The chemical name contains the term "androst", assuming that there is some sort of ene group on ring A. But there does not seem to be such mention of an ene group on ring A. Therefore, the term androst should be androstan. But if this is the case, the 2-cyano group needs to be stated as alpha or beta. This makes a big difference, since usually C2-alpha groups are significantly more effective than beta. 

There are studies about other 2-cyano steroids such as 2-cyano-DHT and 2-cyano-progesterone. In separate studies, one done on dogs, it was seen that both of these 2-cyano steroids caused inhibition of 3b-HSD enzyme. This inhibition would cause severe adrenal suppression. This is a very unsafe inhibition. Whether it occurs in this cyano steroid is unknown, but users need to be aware of this possibility.